What’s next for DTx?

Akili Interactive recently filed an illuminating S-4 along their journey to the public markets. Should the deal go through, Akili will join the ranks of publicly-traded digital therapeutics (DTx) companies Pear Therapeutics and Better Therapeutics—an accomplishment certainly, but with significant hurdles still ahead.

DTx for behavioral health conditions, specifically, are on the march. Companies like Akili, Pear, BehaVR, OxfordVR, AppliedVR, and XRHealth are still in the early phases of go-to-market: building awareness around efficacy with therapists and the provider community. Negotiations with payers and PBMs are still nascent for most DTx, and will be until awareness leads to broader scale adoption. These companies are betting that their investments in R&D will pay off, and match the emergence of a strong market for their products. The timing of these factors coming together—clinical validation, provider and patient adoption at scale, and reimbursement pathways—will separate winners and losers in this space.

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